I started feeding him this a little late after I received it, as I had already finished the ubiquinol I was giving him. For the first month, I mixed two-thirds of it into his breakfast once a day. The powder is fine, so I mixed it into his wet food and he didn't show any resistance from day one. Since nutritional supplements are only effective when given consistently, I plan to continue to do so. Since NMN is a nutritional supplement I've always been interested in, I have high expectations.